Anticonvulsant Effect of Resveratrol against Pentylenetetrazole Induced- Epilepsy in Rats: Role of Nitric Oxide

نویسنده

  • Amany N. Ibrahim
چکیده

INTRODUCTION Epilepsy and seizures disorders affect 50 million people around the world and contribute to morbidity and mortality [1]. The use of antiepileptic drugs is limited due to the vast array of adverse effects. Such as cognitive impairment, effective disorders and recurring seizures [2]. Hence, there is a need for the development of new antiepileptic drugs with fewer adverse effects and high efficacy. Pentylenetetrazole, a prototype chemoconvulsant, is commonly employed for inducing experimental

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تاریخ انتشار 2014